General Information of Drug (ID: DM6R34M)

Drug Name
N-{4 Drug Info
Synonyms
LGB321; CHEMBL3105022; 1210417-75-6; N-{4-[(3r,4r,5s)-3-Amino-4-Hydroxy-5-Methylpiperidin-1-Yl]pyridin-3-Yl}-6-(2,6-Difluorophenyl)-5-Fluoropyridine-2-Carboxamide; N-[4-[(3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl]pyridin-3-yl]-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide; NVP-LGB321; GTPL9367; SCHEMBL1711617; BDBM106896; EX-A1572; AMX10208; SB19299; n-(4-((3r,4r,5s)-3-amino-4-hydroxy-5-methylpiperidin-1-yl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide; US8592455, 96; LGB321 1210415-88-5; N-{4
Cross-matching ID
PubChem CID
46179018
TTD Drug ID
DM6R34M

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PIM-3 protein kinase (PIM3) TTCGOIN PIM3_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PIM-3 protein kinase (PIM3) DTT PIM3 7.86E-06 0.78 3.44
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Kinase inhibitors and methods of their use. US8592455.