Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM6WN2D)

Drug Name
ABT-308 Drug Info
Indication
Disease Entry ICD 11 Status REF
Eosinophilic esophagitis DA24.1 Phase 2 [1]
Asthma CA23 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DM6WN2D

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin 13 receptor alpha-2 (IL13RA2) TTMPZ7V I13R2_HUMAN Antagonist [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Eosinophilic esophagitis
ICD Disease Classification DA24.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin 13 receptor alpha-2 (IL13RA2) DTT IL13RA2 4.40E-01 2.46 1
Interleukin 13 receptor alpha-2 (IL13RA2) DTT IL13RA2 5.77E-05 4.14 2.11
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 ClinicalTrials.gov (NCT00986037) Assessment of the Safety of ABT-308 in Healthy Volunteers and Subjects With Asthma. U.S. National Institutes of Health.