Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM7EUK3)

• Drug Name: Delapril Drug Info
• Synonyms: Adecut (TN)

Indication

Disease Entry	ICD 11	Status	REF
Cardiovascular disease	BA00-BE2Z	Approved	[1]

• Cross-matching ID:
  PubChem CID: 5362116
  ChEBI ID: CHEBI:135735
  CAS Number: CAS 83435-66-9
  TTD Drug ID: DM7EUK3

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Angiotensin-converting enzyme (ACE)	TTL69WB	ACE_HUMAN	Modulator	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Angiotensin-converting enzyme (ACE)	DTT	SLC33A1	2.561	2.511	2.379	7.031

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Cardiovascular disease
• ICD Disease Classification: BA00-BE2Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Angiotensin-converting enzyme (ACE)	DTT	SLC33A1	2.62E-01	-0.01	-0.06

References

• [1] Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.