Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM7R3N5)

Drug Name
Mirikizumab Drug Info
Indication
Disease Entry ICD 11 Status REF
Ulcerative colitis DD71 Approved [1]
Psoriasis vulgaris EA90 Phase 3 [2]
Cross-matching ID
TTD Drug ID
DM7R3N5

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-12 alpha (IL12A) TTRTK6Y IL12A_HUMAN Inhibitor [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Interleukin-12 alpha (IL12A) DTT IL12A 5.206 4.358 4.154 4.868
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Ulcerative colitis
ICD Disease Classification DD71
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin-12 alpha (IL12A) DTT IL12A 2.40E-03 0.29 1
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 761279
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)