Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM7YB08)

Drug Name
SYL-040003 Drug Info
Synonyms SYL-04003; Carbonic anhydrase targeting siRNA (ocular hypertension), Sylentis
Indication
Disease Entry ICD 11 Status REF
Ocular hypertension 9C61.01 Investigative [1]
Cross-matching ID
TTD Drug ID
DM7YB08

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Carbonic anhydrase IV (CA-IV) TTZHA0O CAH4_HUMAN Not Available [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Ocular hypertension
ICD Disease Classification 9C61.01
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Carbonic anhydrase IV (CA-IV) DTT CA4 1.58E-77 -2.02 -1.77
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2599).