Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM83L5Y)

Drug Name

RIP Drug Info

Synonyms

beta-D-Ribopyranose; Ribose(Pyranose Form); 7296-60-8; UNII-49X539P7H4; CHEBI:27476; 49X539P7H4; (2R,3R,4R,5R)-oxane-2,3,4,5-tetrol; b-Ribopyranose; 115794-07-5; beta-D-Ribopyranose (9CI); 1ogd; 1drk; 2dri; 1drj; Ribopyranose, beta-D-; SCHEMBL625216; AC1L9B91; CHEMBL1159662; CTK4A9488; ZINC4097544; DB04286; 1577-EP2301533A1; 1577-EP2292630A1; 1577-EP2316459A1; 1577-EP2305808A1; 1577-EP2281563A1; C08353; 1577-EP2270015A1; 31308-EP2311817A1; 31308-EP2308858A1; 31308-EP2274983A1; 31308-EP2311816A1; 31308-EP2292088A1

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 441481
ChEBI ID: CHEBI:27476
CAS Number: CAS 7296-60-8
TTD Drug ID: DM83L5Y

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Angiotensin-converting enzyme (ACE)	TTL69WB	ACE_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Angiotensin-converting enzyme (ACE)	DTT	SLC33A1	2.561	2.511	2.379	7.031

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Angiotensin-converting enzyme (ACE)	DTT	SLC33A1	2.62E-01	-0.01	-0.06

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Difluorostatine- and difluorostatone-containing peptides as potent and specific renin inhibitors. J Med Chem. 1985 Nov;28(11):1553-5.