Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM83MOK)

Drug Name
Glassia Drug Info
Synonyms Glassia (TN)
Indication
Disease Entry ICD 11 Status REF
Emphysema CA21 Approved [1]
Cross-matching ID
TTD Drug ID
DM83MOK

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Alpha-1-antitrypsin (SERPINA1) TTA7UJC A1AT_HUMAN Inhibitor [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Alpha-1-antitrypsin (SERPINA1) DTT SERPINA1 12.865 6.98 11.766 10.09
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Emphysema
ICD Disease Classification CA21
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Alpha-1-antitrypsin (SERPINA1) DTT SERPINA1 7.84E-01 -0.08 -0.1
Alpha-1-antitrypsin (SERPINA1) DTT SERPINA1 1.32E-03 0.33 0.54
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7487).
2 Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.