Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM872CU)

Drug Name
DuP-983 Drug Info
Indication
Disease Entry ICD 11 Status REF
Pruritus EC90 Terminated [1]
Cross-matching ID
TTD Drug ID
DM872CU

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cytochrome P450 reductase (P450) TTOQ9GZ NCPR_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Cytochrome P450 reductase (P450) DTT POR 9.429 6.313 7.325 7.047
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Pruritus
ICD Disease Classification EC90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cytochrome P450 reductase (P450) DTT POR 6.22E-08 0.29 0.46
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003352)
2 CN patent application no. 1096855, Composition produced by treatment and induction of nitrogen mono oxide synthase expressed matter, and use thereof.