Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8GHT2)

Drug Name
DBO-11 Drug Info
Synonyms 166374-49-8; Naxifylline (USAN/INN)
Indication
Disease Entry ICD 11 Status REF
Cancer related pain MG30 Terminated [1]
Therapeutic Class
Analgesics
Cross-matching ID
PubChem CID
23724971
TTD Drug ID
DM8GHT2

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Opioid receptor mu (MOP) TTKWM86 OPRM_HUMAN Agonist [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Opioid receptor mu (MOP) DTT OPRM1 4.548 5.062 4.652 4.776
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Cancer related pain
ICD Disease Classification MG30
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Opioid receptor mu (MOP) DTT OPRM1 5.94E-01 -0.02 -0.17
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009577)
2 Emerging analgesics in cancer pain management. Expert Opin Emerg Drugs. 2005 Feb;10(1):151-71.