Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8L1GJ)

Drug Name
SNA-125 Drug Info
Indication
Disease Entry ICD 11 Status REF
Atopic dermatitis EA80 Phase 1 [1]
Pruritus EC90 Phase 1 [1]
Psoriasis vulgaris EA90 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM8L1GJ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Janus kinase 3 (JAK-3) TTT7PJU JAK3_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Janus kinase 3 (JAK-3) DTT JAK3 2.104 3.248 2.848 4.485
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Atopic dermatitis
ICD Disease Classification EA80
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Janus kinase 3 (JAK-3) DTT JAK3 4.94E-03 0.28 1.41
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)