Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8M0N9)

Drug Name

4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone Drug Info

Synonyms

CHEMBL199829; Sulfonamide chalcone, 5; SCHEMBL3484418; BDBM50174837; 4''-(p-toluenesulfonamide)-3,4-dihydroxy chalcone

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Intestinal maltase-glucoamylase (MGAM)	TTXWASR	MGA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Intestinal maltase-glucoamylase (MGAM)	DTT	MGAM	4.59E-01	-0.02	-0.24

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Sulfonamide chalcone as a new class of alpha-glucosidase inhibitors. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5514-6.