Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8N7BA)

Drug Name
BVT 933 Drug Info
Indication
Disease Entry ICD 11 Status REF
Obesity 5B81 Investigative [1]
Cross-matching ID
TTD Drug ID
DM8N7BA

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 2C receptor (HTR2C) TTWJBZ5 5HT2C_HUMAN Antagonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
5-HT 2C receptor (HTR2C) DTT HTR2C 4.233 3.329 3.843 3.888
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Obesity
ICD Disease Classification 5B81
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
5-HT 2C receptor (HTR2C) DTT HTR2C 1.02E-02 -0.45 -0.37
5-HT 2C receptor (HTR2C) DTT HTR2C 2.27E-01 0.27 0.6
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Obesity: pathophysiology and clinical management. Curr Med Chem. 2009;16(4):506-21.