Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8OYI4)

Drug Name
Platinum IV complexe 1 Drug Info
Synonyms PMID26394986-Compound-69
Cross-matching ID
TTD Drug ID
DM8OYI4

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Signal transducer and activator of transcription 1 (STAT1) TTN7R6K STAT1_HUMAN Inhibitor [1]
Signal transducer and activator of transcription 3 (STAT3) TTH8FZW STAT3_HUMAN Inhibitor [1]
Signal transducer and activator of transcription 5 (STAT5) TTLRFIH STA5A_HUMAN; STA5B_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Signal transducer and activator of transcription 3 (STAT3) DTT STAT3 9.537 8.097 9.732 8.128
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Signal transducer and activator of transcription 3 (STAT3) DTT STAT3 6.50E-03 -0.12 -0.21
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A STAT inhibitor patent review: progress since 2011.Expert Opin Ther Pat. 2015;25(12):1397-421.