General Information of Drug (ID: DM8PNKC)

Drug Name
N-(5-methylthiazol-2-yl)-2-phenylacetamide Drug Info
Synonyms N-(5-methyl-1,3-thiazol-2-yl)-2-phenylacetamide; AC1NMTHK; CHEMBL425300; MolPort-006-386-848; ZINC3160947; STK408984; AKOS003243303; MCULE-9670423324; ST004442
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5015763
TTD Drug ID
DM8PNKC

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
LOX-5 messenger RNA (ALOX5 mRNA) TTSJ6Q4 LOX5_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
LOX-5 messenger RNA (ALOX5 mRNA) DTT ALOX5 4.966 5.133 5.358 6.128
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
LOX-5 messenger RNA (ALOX5 mRNA) DTT ALOX5 9.43E-03 0.14 0.28
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening. J Med Chem. 2007 May 31;50(11):2640-6.