Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM8SINB)

Drug Name
SDZ-LAV-694 Drug Info
Synonyms LAV-694; 6-[2-(2,5-Dimethoxyphenyl)ethyl]-4-ethylquinazoline
Indication
Disease Entry ICD 11 Status REF
Actinic keratosis EK90.0 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM8SINB

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tubulin (TUB) TTML2WA NOUNIPROTAC Inhibitor [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Tubulin (TUB) DTT TUB 7.743 8.411 8.625 8.347
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Actinic keratosis
ICD Disease Classification EK90.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tubulin (TUB) DTT NO-GeName 7.94E-02 0.35 0.43
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Recent patents reveal microtubules as persistent promising target for novel drug development for cancers. Recent Pat Antiinfect Drug Discov. 2009 Nov;4(3):164-82.
2 Recent Patents Reveal Microtubules as Persistent Promising Target for Novel Drug Development for Cancers. Recent Patents on Anti-Infective Drug Discovery 12/2009; 4(3):164-82.