Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM93DYT)

Drug Name

2-methoxy-3,4-methylenedioxybenzophenone Drug Info

Synonyms

872881-74-8; (4-methoxybenzo[d][1,3]dioxol-5-yl)(phenyl)methanone; 2-methoxy-3,4-methylenedioxybenzophenone; CHEMBL497717; CTK3C4926; SUKAEERDMQPLMM-UHFFFAOYSA-; DTXSID20475539; AKOS027335527; 4-Methoxy-5-benzoyl-1,3-benzodioxole; Methanone, (4-methoxy-1,3-benzodioxol-5-yl)phenyl-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 11999967
CAS Number: CAS 872881-74-8
TTD Drug ID: DM93DYT

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Liver carboxylesterase (CES1)	TTMF541	EST1_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Liver carboxylesterase (CES1)	DTT	CES1	12.04	6.525	5.311	5.909

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Liver carboxylesterase (CES1)	DTT	CES1	3.82E-08	1.86	1.9

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Phenolic compounds from the roots of Lindera fruticosa. J Nat Prod. 2006 May;69(5):853-5.