Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM9EA3C)

Drug Name

6-tert-butyl-m-cresol Drug Info

Synonyms

6-tert-Butyl-m-cresol; 2-tert-Butyl-5-methylphenol; 88-60-8; 6-tert-Butyl-3-methylphenol; 2-(tert-butyl)-5-methylphenol; m-Cresol, 6-tert-butyl-; Phenol, 2-(1,1-dimethylethyl)-5-methyl-; 5-Methyl-2-tert-butylphenol; 3-Methyl-6-tert-butylphenol; UNII-UXV32MJ2CA; 2-tert-butyl-5-methyl-phenol; 6-t-butyl-m-cresol; HSDB 5260; EINECS 201-842-3; NSC 48467; UXV32MJ2CA; 2-t-Butyl-5-methylphenol; BRN 1908225; Benzene, 1-tert-butyl-2-hydroxy-4-methyl-; 2-(1,1-DIMETHYLETHYL)-5-METHYLPHENOL; Phenol, 2-tert-butyl-5-methyl-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6937
CAS Number: CAS 88-60-8
TTD Drug ID: DM9EA3C

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Transient receptor potential cation channel V3 (TRPV3)	TT946IA	TRPV3_HUMAN	Activator	[2]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Transient receptor potential cation channel V3 (TRPV3)	DTT	TRPV3	7.58E-01	5.28E-03	0.05

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4111).
2	Monoterpenoid agonists of TRPV3. Br J Pharmacol. 2007 Jun;151(4):530-40.