Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM9F7R0)

Drug Name

SBP-002 Drug Info

Synonyms

Coramsine; Solasonine + solamargine; Solasodine glycosides (cancer, injectable formulation), Solbec; Solasodine glycosides (psoriasis, cream formulation), Solbec; Solasonine + solamargine (cancer), Solbec; Solasonine + solamargine (psoriasis), Solbec; SBP-002 (intravenous, cancer), Solbec; SBP-002 (psoriasis, cream formulation), Solbec

Indication

Disease Entry	ICD 11	Status	REF
Melanoma	2C30	Terminated	[1]

Cross-matching ID

TTD Drug ID: DM9F7R0

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukin 6 receptor (IL6R)	TT0E5SK	IL6RA_HUMAN; IL6RB_HUMAN	Modulator	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Interleukin 6 receptor (IL6R)	DTT	IL6R	6.42	5.564	5.031	5.404

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Melanoma

ICD Disease Classification

2C30

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Interleukin 6 receptor (IL6R)	DTT	IL6R; IL6ST	5.77E-01	-0.24	-0.47

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022850)
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.