General Information of Drug (ID: DM9GJAY)

Drug Name
6-iodo-4'-methylaminoflavone Drug Info
Synonyms
6-iodo-4'-methylaminoflavone; 871101-30-3; CHEMBL224643; 6-iodo-2-(4-methylaminophenyl)-chromen-4-one; SCHEMBL4991516; 6-iodo-4''-methylaminoflavone; DTXSID20469771; QIZWRTNISFPGTO-UHFFFAOYSA-N; ZINC13675690; BDBM50176896; KB-248886
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
11632242
CAS Number
CAS 871101-30-3
TTD Drug ID
DM9GJAY

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Amyloid beta A4 protein (APP) TTE4KHA A4_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Amyloid beta A4 protein (APP) DTT APP 6.473 8.014 8.631 7.57
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Amyloid beta A4 protein (APP) DTT APP 1.60E-02 -0.07 -0.31
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Radioiodinated flavones for in vivo imaging of beta-amyloid plaques in the brain. J Med Chem. 2005 Nov 17;48(23):7253-60.