Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM9KCYQ)

• Drug Name: L-709,587 Drug Info
• Synonyms: L-709,587; C32-O-(1-METHYL-INDOL-5-YL) 18-HYDROXY-ASCOMYCIN; 1qpl; DB03621

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 5496872
  TTD Drug ID: DM9KCYQ

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
FK506-binding protein 1A (FKBP1A)	TTMW94E	FKB1A_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
FK506-binding protein 1A (FKBP1A)	DTT	FKBP1A	7.78	7.914	8.23	7.689

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
FK506-binding protein 1A (FKBP1A)	DTT	FKBP1A	9.70E-01	-0.04	-0.09

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.