Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM9OA35)

Drug Name
Long-acting erythropoietin conjugate Drug Info
Synonyms HM-10760; HM-10760A; LAPS-EPO; Long-acting erythropoietin conjugate (LAPS, anemia); Long-acting erythropoietin conjugate (LAPS, anemia), Hanmi
Indication
Disease Entry ICD 11 Status REF
Anemia 3A00-3A9Z Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM9OA35

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Erythropoietin (EPO) TTQG4NR EPO_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Erythropoietin (EPO) DTT EPO 4.717 3.225 1 3.781
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Anemia
ICD Disease Classification 3A00-3A9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Erythropoietin (EPO) DTT EPO 5.72E-01 -0.15 -0.83
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT01030315) A Study of HM10760A (Long-acting Erythropoietin) in Healthy Adult Caucasian and Japanese Subjects. U.S. National Institutes of Health.
2 Company report (Pharmexcil)