Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM9R5J6)

Drug Name

Tezepelumab Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Severe asthma	CA23	Approved	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Thymic stromal lymphopoietin (TSLP)	TTHMW3T	TSLP_HUMAN	Not Available	[2]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Severe asthma

ICD Disease Classification

CA23

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Thymic stromal lymphopoietin (TSLP)	DTT	TSLP	8.89E-01	0.3	0.26

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 761224.
2	Tezepelumab in Adults with Uncontrolled Asthma. N Engl J Med. 2017 Sep 7;377(10):936-946.