Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMA15WU)

Drug Name

(2-(4-chlorobenzyloxy)-5-bromophenyl)methanamine Drug Info

Synonyms

CHEMBL233845; (2-(4-chlorobenzyloxy)-5-bromophenyl)methanamine; SCHEMBL5699914; [5-bromo-2-[(4-chlorophenyl)methoxy]phenyl]methanamine; BDBM50205765; AKOS010099713; Benzenemethanamine, 5-bromo-2-[(4-chlorophenyl)methoxy]-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 11267381
TTD Drug ID: DMA15WU

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
C-C chemokine receptor type 5 (CCR5)	TT2CEJG	CCR5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
C-C chemokine receptor type 5 (CCR5)	DTT	CCR5	9.30E-01	-0.08	-0.11

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	CCR5 receptor antagonists: discovery and SAR of novel 4-hydroxypiperidine derivatives. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1883-7.