Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMA7LUR)

Drug Name

ANTAQ Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Puromycin-sensitive aminopeptidase (NPEPPS)	TT371QC	PSA_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Puromycin-sensitive aminopeptidase (NPEPPS)	DTT	NPEPPS	6.142	6.779	6.6	6.838

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Puromycin-sensitive aminopeptidase (NPEPPS)	DTT	NPEPPS	8.88E-01	7.78E-03	1.30E-02

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Fluorescent bioprobes for visualization of puromycin-sensitive aminopeptidase in living cells. Bioorg Med Chem Lett. 2003 Jan 6;13(1):83-6.