Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMBP1TQ)

Drug Name
2-(2-(2-chlorophenoxy)phenyl)acetic acid Drug Info
Synonyms CHEMBL30038; 2-(2-(2-chlorophenoxy)phenyl)acetic acid; BDBM50295282; ZINC28766380; [2-(2-Chloro-phenoxy)-phenyl]-acetic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
15581854
CAS Number
CAS 81682-40-8
TTD Drug ID
DMBP1TQ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-8 (IL8) TTCTE1G IL8_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Interleukin-8 (IL8) DTT CXCL8 4.892 4.17 4.65 3.807
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin-8 (IL8) DTT CXCL8 9.05E-17 2.09 3.08
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4026-30.