Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMBY6CQ)

Drug Name
SDZ-87-469 Drug Info
Synonyms SDZ-87-469; AC1OCEZP; CHEMBL328466; SCHEMBL10689408; SDZ-87469
Indication
Disease Entry ICD 11 Status REF
Coronary artery disease BA80 Terminated [1]
Cross-matching ID
PubChem CID
6918069
TTD Drug ID
DMBY6CQ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Squalene monooxygenase (SQLE) TTE14XG ERG1_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Squalene monooxygenase (SQLE) DTT SQLE 4.638 5.984 5.744 5.626
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Coronary artery disease
ICD Disease Classification BA80
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Squalene monooxygenase (SQLE) DTT SQLE 7.14E-03 0.45 2.51
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Chemotherapy of fungal diseases. 1990. Page(525-550).
2 Effects of squalene epoxidase inhibitors on Candida albicans. Antimicrob Agents Chemother. 1992 Aug;36(8):1779-81.