Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMC1A42)

Drug Name

SUN-11031 Drug Info

Synonyms

6,6,6-trifluoromethionine; AC1L5KZ2; SCHEMBL245985; CTK1D7491; NSC73030; NSC-73030; 2-Amino-4-(trifluoromethylthio)butyric acid; 2-amino-4-(trifluoromethylsulfanyl)butanoic acid

Indication

Disease Entry	ICD 11	Status	REF
Anorexia nervosa cachexia	6B80	Terminated	[1]

Cross-matching ID

PubChem CID: 251951
TTD Drug ID: DMC1A42

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Growth hormone secretagogue receptor 1 (GHSR)	TTWDC17	GHSR_HUMAN	Agonist	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Growth hormone secretagogue receptor 1 (GHSR)	DTT	GHSR	2.609	4.104	4.797	1.485

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Anorexia nervosa cachexia

ICD Disease Classification

6B80

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Growth hormone secretagogue receptor 1 (GHSR)	DTT	GHSR	4.56E-01	-0.14	-0.74

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Emerging drugs for eating disorder treatment. Expert Opin Emerg Drugs. 2006 May;11(2):315-36.