Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMCJMOS)

Drug Name
ALN-PCS Drug Info
Indication
Disease Entry ICD 11 Status REF
Hypercholesterolaemia 5C80.0 Preclinical [1]
Cross-matching ID
TTD Drug ID
DMCJMOS

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PCSK9 messenger RNA (PCSK9 mRNA) TTNIZ2B PCSK9_HUMAN Not Available [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Hypercholesterolaemia
ICD Disease Classification 5C80.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PCSK9 messenger RNA (PCSK9 mRNA) DTT PCSK9 4.82E-02 -0.07 -0.3
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of Alnylam Pharmaceuticals, Inc (2011).