Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMCM239)

Drug Name
Larotaxel Drug Info
Synonyms Benzenepropanoic acid; PNU 100940; XRP 9881; XRP9881
Indication
Disease Entry ICD 11 Status REF
Bladder cancer 2C94 Discontinued in Phase 3 [1]
Pancreatic cancer 2C10 Discontinued in Phase 3 [1]
Cross-matching ID
PubChem CID
6918260
CAS Number
CAS 156294-36-9
TTD Drug ID
DMCM239

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tubulin (TUB) TTML2WA NOUNIPROTAC Inhibitor [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Tubulin (TUB) DTT TUB 7.743 8.411 8.625 8.347
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Bladder cancer
ICD Disease Classification 2C94
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tubulin (TUB) DTT NO-GeName 7.94E-02 0.35 0.43
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010227)
2 Pharma & Vaccines. Product Development Pipeline. April 29 2009.