Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMD32IN)

Drug Name

Long-acting FSH conjugate Drug Info

Synonyms

HM-12160B; LAPS-FSH; Long-acting FSH conjugate (LAPS); Long-acting FSH conjugate (LAPS), Hanmi; Long-acting follicle-stimulating hormone conjugate (LAPS, female infertility), Hanmi

Indication

Disease Entry	ICD 11	Status	REF
Female infertility	GA31.Z	Investigative	[1]

Cross-matching ID

TTD Drug ID: DMD32IN

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Follicle-stimulating hormone receptor (FSHR)	TTZFDBT	FSHR_HUMAN	Modulator	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Follicle-stimulating hormone receptor (FSHR)	DTT	FSHR	3.233	3.945	3.392	4.426

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Female infertility

ICD Disease Classification

GA31.Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Follicle-stimulating hormone receptor (FSHR)	DTT	FSHR	1.56E-02	-0.56	-1.34

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 253).