Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMD8TNK)

Drug Name
XL475 Drug Info
Indication
Disease Entry ICD 11 Status REF
Type-2 diabetes 5A11 Preclinical [1]
Cross-matching ID
TTD Drug ID
DMD8TNK

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
G-protein coupled bile acid receptor 1 (GPBAR1) TTSDVTR GPBAR_HUMAN Agonist [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Type-2 diabetes
ICD Disease Classification 5A11
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
G-protein coupled bile acid receptor 1 (GPBAR1) DTT GPBAR1 4.60E-01 0.02 0.09
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of Exelixis (2011).