Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDK4MG)

Drug Name

M7583 Drug Info

Synonyms

ZAXMFSSGOARPBM-UHFFFAOYSA-N; 51123-09-2; 5-amino-n-ethyl-2-methyl-n-phenylbenzenesulfonamide; 5-Amino-N-ethyl-2-methyl-N-phenylbenzenesulphonamide; 4-AMINO TOLUENE-2-(N-ETHYL) SULFONANILIDE; 5-AMINO-N-ETHYL-O-TOLUENESULFONANILIDE; Q-200530; AMINO-4-METHYL-BENZENE-3-(N-ETHYL)-SULFANILIDE; 5-amino-N-ethyl-2-methyl-N-phenylbenzene-1-sulfonamide; NSC84161; EINECS 256-998-5; NSC 84161; AC1Q2YPH; AC1L3WX0; AC1Q6V7C; AC1Q2YP6; SCHEMBL9072675; 4-Aminotoluol-2-sulfethylanilid; Benzenesulfonamide, 3-amino-N-ethyl-6-methyl-N-phenyl-; CTK4J3696; MolPort-001-759-851

Indication

Disease Entry	ICD 11	Status	REF
Haematological malignancy	2B33.Y	Phase 1	[1]

Cross-matching ID

PubChem CID: 96649
CAS Number: CAS 51123-09-2
TTD Drug ID: DMDK4MG

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosine-protein kinase BTK (ATK)	TTGM6VW	BTK_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tyrosine-protein kinase BTK (ATK)	DTT	BTK	3.838	3.897	5.053	5.897

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Haematological malignancy

ICD Disease Classification

2B33.Y

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tyrosine-protein kinase BTK (ATK)	DTT	BTK	3.54E-01	0.24	0.56

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)