Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDNHRA)

Drug Name
Ilodecakin Drug Info
Synonyms Prevascar; Ilodecakin, Renovo; Recombinant IL-10 (scarring), Renovo
Indication
Disease Entry ICD 11 Status REF
Sarcoidosis 4B20.5 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMDNHRA

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-10 (IL10) TTT0Q1F IL10_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Interleukin-10 (IL10) DTT IL10 5.87 4.853 5.092 5.629
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Sarcoidosis
ICD Disease Classification 4B20.5
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin-10 (IL10) DTT IL10 1.07E-02 0.08 0.56
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT00984646) Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10). U.S. National Institutes of Health.
2 Ilodecakin. Schering-Plough Corp. IDrugs. 1999 Oct;2(10):1045-58.