Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDUW9F)

Drug Name

Sulfamic acid 4-benzoyl-phenyl ester Drug Info

Synonyms

CHEMBL304708; Sulfamic acid 4-benzoyl-phenyl ester; SCHEMBL9451248; 4-(Aminosulfonyloxy)benzophenone; LWUJBMNPWUQTGS-UHFFFAOYSA-N; Sulfamic acid 4-benzoylphenyl ester

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 9817055
TTD Drug ID: DMDUW9F

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Steryl-sulfatase (STS)	TTHM0R1	STS_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Steryl-sulfatase (STS)	DTT	STS	4.722	6.048	5.125	4.768

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Steryl-sulfatase (STS)	DTT	STS	1.80E-38	-0.79	-1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	4,4'-Benzophenone-O,O'-disulfamate: a potent inhibitor of steroid sulfatase. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2093-5.