Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMDZ9BY)

Drug Name

N-(5-Sulfamoyl-[1,3,4]thiadiazol-2-yl)-benzamide Drug Info

Synonyms

NSC698990; CHEMBL281376; N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)benzamide; 86029-44-9; N-(2-sulfamoyl-1,3,4-thiadiazol-5-yl)benzamide; Benzamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-; SCHEMBL9795960; AC1L997Y; BDBM16669; CTK2I3789; DTXSID30327878; ZINC5925092; heterocyclic sulfonamide compound 34; AKOS030579978; NSC-698990; NCI60_035393; LS-25666; 2-benzoylamino-1,3,4-thiadiazole 5-sulfonamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 394898
CAS Number: CAS 86029-44-9
TTD Drug ID: DMDZ9BY

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase IV (CA-IV)	TTZHA0O	CAH4_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase IV (CA-IV)	DTT	CA4	1.58E-77	-2.02	-1.77

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties. J Med Chem. 2002 Jan 17;45(2):312-20.