Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DME2PFQ)

Drug Name
TA-106 Drug Info
Synonyms FAb antibody fragment (inflammation), Taligen Therapeutics; Anti-factor B FAb (inflammation), Alexion
Indication
Disease Entry ICD 11 Status REF
Asthma CA23 Investigative [1]
Cross-matching ID
TTD Drug ID
DME2PFQ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement factor B (CFB) TTA0P7K CFAB_HUMAN Not Available [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Complement factor B (CFB) DTT CFB 10.419 4.895 7.235 6.78
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 12 Disease of the respiratory system
Disease Class ICD-11: CA23 Asthma
The Studied Tissue Nasal and bronchial airway
The Studied Disease Asthma [ICD-11:CA23]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement factor B (CFB) DTT CFB 1.63E-02 0.07 0.13
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2339).