Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMEF32D)

Drug Name
TQ-1017 Drug Info
Indication
Disease Entry ICD 11 Status REF
Pain MG30-MG3Z Investigative [1]
Cross-matching ID
TTD Drug ID
DMEF32D

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 2C receptor (HTR2C) TTWJBZ5 5HT2C_HUMAN Agonist [1]
Norepinephrine transporter (NET) TTAWNKZ SC6A2_HUMAN Agonist [1]
Opioid receptor mu (MOP) TTKWM86 OPRM_HUMAN Agonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
5-HT 2C receptor (HTR2C) DTT HTR2C 4.233 3.329 3.843 3.888
Opioid receptor mu (MOP) DTT OPRM1 4.548 5.062 4.652 4.776
Norepinephrine transporter (NET) DTT SLC6A2 2.459 3.426 3.322 3.35
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Pain
ICD Disease Classification MG30-MG3Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
5-HT 2C receptor (HTR2C) DTT HTR2C 1.02E-02 -0.45 -0.37
5-HT 2C receptor (HTR2C) DTT HTR2C 2.27E-01 0.27 0.6
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015