Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMET9ZC)

Drug Name
Phosphoric acid mono-((E)-tetradec-11-enyl) ester Drug Info
Synonyms CHEMBL188591; SCHEMBL193531; Phosphoric acid mono-((E)-tetradec-11-enyl) ester; ZINC13648502
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
11312382
TTD Drug ID
DMET9ZC

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lysophosphatidic acid receptor 1 (LPAR1) TTQ6S1K LPAR1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Lysophosphatidic acid receptor 1 (LPAR1) DTT LPAR1 5.998 6.919 6.589 6.975
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Lysophosphatidic acid receptor 1 (LPAR1) DTT LPAR1 6.48E-01 -0.04 -0.24
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activ... J Med Chem. 2005 Jul 28;48(15):4919-30.