General Information of Drug (ID: DMEVT4I)

Drug Name
ART-144 Drug Info
Synonyms Anti-inflammatory agent (intra-articular/injectable, sustained release, osteoarthritis), Artyx pharmaceuticals
Indication
Disease Entry ICD 11 Status REF
Osteoarthritis FA00-FA05 Investigative [1]
Cross-matching ID
TTD Drug ID
DMEVT4I

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Transforming growth factor beta 1 (TGFB1) TTR9XHZ TGFB1_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Transforming growth factor beta 1 (TGFB1) DTT TGFB1 5.844 5.859 6.44 6.172
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Osteoarthritis
ICD Disease Classification FA00-FA05
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Transforming growth factor beta 1 (TGFB1) DTT TGFB1 5.95E-09 1.68 7.81
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Pharmaceutical products of TORREYA partners. December 2011.