Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFDERP)

Drug Name
PMID28870136-Compound-52 Drug Info
Cross-matching ID
PubChem CID
2519
ChEBI ID
CHEBI:27732
CAS Number
CAS 58-08-2
TTD Drug ID
DMFDERP
ACDINA Drug ID
D00088

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ecto-5'-nucleotidase (CD73) TTK0O6Y 5NTD_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Ecto-5'-nucleotidase (CD73) DTT NT5E 6.505 5.166 5.198 6.89
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Ecto-5'-nucleotidase (CD73) DTT NT5E 9.56E-01 0.33 0.37
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Ectonucleotidase inhibitors: a patent review (2011-2016).Expert Opin Ther Pat. 2017 Dec;27(12):1291-1304.