Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFJ0ZA)

Drug Name
GSK-326416 Drug Info
Indication
Disease Entry ICD 11 Status REF
Gastroparesis DA41.00 Preclinical [1]
Cross-matching ID
TTD Drug ID
DMFJ0ZA

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Motilin receptor (MLNR) TT953CX MTLR_HUMAN Agonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Motilin receptor (MLNR) DTT MLNR 1.807 2 3.17 5.087
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Gastroparesis
ICD Disease Classification DA41.00
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Motilin receptor (MLNR) DTT MLNR 6.35E-02 -0.06 -0.27
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Emerging drugs for postoperative ileus. Expert Opin Emerg Drugs. 2007 Nov;12(4):619-26.