Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFLUTR)

Drug Name
Glucagon recombinant Drug Info
Synonyms Glucagon recombinant; GTPL1136; CHEMBL266481
Indication
Disease Entry ICD 11 Status REF
Hypoglycemia 5A41 Approved [1]
Short bowel syndrome KB89.1 Approved [2]
Therapeutic Class
Antihypoglycemic Agents
Cross-matching ID
PubChem CID
44278361
ChEBI ID
CHEBI:5391
TTD Drug ID
DMFLUTR

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucagon receptor (GCGR) TT9O6WS GLR_HUMAN Binder [3]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Glucagon receptor (GCGR) DTT GCGR 4.695 1.926 1.322 3.797
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Hypoglycemia
ICD Disease Classification 5A41
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glucagon receptor (GCGR) DTT GCGR 7.24E-02 -0.52 -0.92
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2 Where are we at with short bowel syndrome and small bowel transplant. World J Transplant. 2012 Dec 24;2(6):95-103.
3 Glucagon receptor expression and glucagon stimulation of ghrelin secretion in rat stomach. Biochem Biophys Res Commun. 2007 Jun 15;357(4):865-70.