Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFN1WI)

Drug Name

BR3-Fc Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Idiopathic thrombocytopenic purpura	3B64.10	Discontinued in Phase 2	[1]
Rheumatoid arthritis	FA20	Discontinued in Phase 2	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
B-cell-activating factor (TNFSF13B)	TTWMIDN	TN13B_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Idiopathic thrombocytopenic purpura

ICD Disease Classification

3B64.10

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
B-cell-activating factor (TNFSF13B)	DTT	TNFSF13B	4.51E-01	0.04	0.09

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54.