Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFRA1Y)

Drug Name

Phenylarsonic acid Drug Info

Synonyms

BENZENEARSONIC ACID; 1998/5/5; Monophenylarsonic acid; Arsonic acid, phenyl-; UNII-57F9KU116M; Kyselina benzenarsonova [Czech]; HSDB 6381; EINECS 202-631-9; NSC 15566; Arsonic acid, As-phenyl-; BRN 2935741; AI3-16050; CHEMBL364571; CHEBI:29851; 57F9KU116M; Kyselina benzenarsonova; C6H7AsO3; benzenarsonic acid; Benzenearsonie acid; ACMC-20ajwq; PhAsO3H2; PhAsO(OH)2; AC1Q1HDM; AC1L1OLG; KSC489M9F; 4-16-00-01183 (Beilstein Handbook Reference); SCHEMBL707127; WLN: Q-AS-QO & DTXSID6059158; CTK3I9692; BDBM26997

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 7365
ChEBI ID: CHEBI:29851
CAS Number: CAS 98-05-5
TTD Drug ID: DMFRA1Y

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase (CA)	TTUNARX	NOUNIPROTAC	Inhibitor	[2]
Carbonic anhydrase IV (CA-IV)	TTZHA0O	CAH4_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase IV (CA-IV)	DTT	CA4	1.58E-77	-2.02	-1.77

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5769-73.
2	Carbonic anhydrase inhibitors: inhibition of the cytosolic human isozyme VII with anions. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3139-43.