Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFUABI)

Drug Name

1-aminohexylphosphonic acid Drug Info

Synonyms

(1-Aminohexyl)phosphonic acid; 1-aminohexylphosphonic Acid; 63207-60-3; CHEMBL40508; 109638-78-0; ACMC-20mcgx; AC1MC01Z; SCHEMBL625939; CTK6D6935; DTXSID70370060; 1-AMINOHEXYL PHOSPHONIC ACID; Phosphonic acid, P-(1-aminohexyl)-; AKOS015892987; DB-054431; FT-0640877

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2733961
CAS Number: CAS 109638-78-0
TTD Drug ID: DMFUABI

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Aminopeptidase N (ANPEP)	TTPHMWB	AMPN_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Aminopeptidase N (ANPEP)	DTT	ANPEP	8.744	7.809	8.914	11.49

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Aminopeptidase N (ANPEP)	DTT	ANPEP	8.84E-07	-0.3	-0.71

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13. Bioorg Med Chem. 2010 Apr 15;18(8):2930-6.