Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMFYM61)

Drug Name
VTP-201227 Drug Info
Indication
Disease Entry ICD 11 Status REF
Psoriatic disorder EA90 Discontinued in Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMFYM61

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cytochrome P450 reductase (P450) TTOQ9GZ NCPR_HUMAN Inhibitor [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Cytochrome P450 reductase (P450) DTT POR 9.429 6.313 7.325 7.047
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Psoriatic disorder
ICD Disease Classification EA90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cytochrome P450 reductase (P450) DTT POR 6.22E-08 0.29 0.46
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022961)
2 VTP-201227. VietMedix.