Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMG5VJF)

Drug Name
L-660771 Drug Info
Synonyms MK-571
Cross-matching ID
PubChem CID
16760063
TTD Drug ID
DMG5VJF
VARIDT Drug ID
DR00555

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leukotriene CysLT1 receptor (CYSLTR1) TTGKOY9 CLTR1_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Leukotriene CysLT1 receptor (CYSLTR1) DTT CYSLTR1 3.233 3.733 -0.152 3.797
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Leukotriene CysLT1 receptor (CYSLTR1) DTT CYSLTR1 1.96E-02 0.24 0.43
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Pharmacology of the leukotriene antagonist verlukast: the (R)-enantiomer of MK-571. Can J Physiol Pharmacol. 1991 Dec;69(12):1847-54.