Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMGD0HT)

• Drug Name: Tellurium Drug Info
• Synonyms: Tellurium; 13494-80-9; Telloy; Tellur; Aurum paradoxum; Tellurium element; Tellur [Polish]; Metallum problematum; Tellurium, metallic; Tellurium, elemental; Tellurium Atom; UNII-NQA0O090ZJ; Tellurium and compounds; HSDB 2532; NCI-C60117; EINECS 236-813-4; NQA0O090ZJ; teluro; Tellurium, 99+%, (trace metal basis), powder; Tellurium, 99.999%, (trace metal basis), powder; tellure; Tellurium compounds, n.o.s.; Tellurium, 99.8%, (trace metal basis), powder, -200 mesh; Tellurium powder; Tellurium compounds; ACMC-1BQVR; 52Te; EC 236-813-4

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 6327182
  ChEBI ID: CHEBI:30452
  CAS Number: CAS 13494-80-9
  TTD Drug ID: DMGD0HT

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Squalene monooxygenase (SQLE)	TTE14XG	ERG1_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Squalene monooxygenase (SQLE)	DTT	SQLE	4.638	5.984	5.744	5.626

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Squalene monooxygenase (SQLE)	DTT	SQLE	7.14E-03	0.45	2.51

References

• [1] Squalene epoxidase as hypocholesterolemic drug target revisited. Prog Lipid Res. 2003 Jan;42(1):37-50.