Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMGID4T)

Drug Name

FP-1102 Drug Info

Synonyms

Farbetics; FP-1101; AOC3 protein inhibitors (incipient vasculopathies), Faron Pharmaceuticals; Vascular adhesion protein 1 inhibitor (incipient vasculopathies), Faron Pharmaceuticals; Vitamin B1 analog (incipient vasculopathies), Faron Pharmaceuticals

Indication

Disease Entry	ICD 11	Status	REF
Vascular disease	BE2Z	Investigative	[1]

Cross-matching ID

TTD Drug ID: DMGID4T

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Membrane copper amine oxidase (AOC3)	TT7HC21	AOC3_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Membrane copper amine oxidase (AOC3)	DTT	AOC3	7.055	8.263	6.709	7.374

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Vascular disease

ICD Disease Classification

BE2Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Membrane copper amine oxidase (AOC3)	DTT	AOC3	8.36E-22	-1.03	-1.54

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).