Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMGL19D)

Drug Name
Enzalutamide Drug Info
Synonyms MDV3100; Enzalutamide (AR inhibitor)
Indication
Disease Entry ICD 11 Status REF
Prostate cancer 2C82.0 Approved [1]
Cross-matching ID
PubChem CID
15951529
ChEBI ID
CHEBI:68534
CAS Number
CAS 915087-33-1
TTD Drug ID
DMGL19D
ACDINA Drug ID
D01051

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Androgen receptor (AR) TTS64P2 ANDR_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Androgen receptor (AR) DTT AR 5.955 4.868 5.902 5.567
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Prostate cancer
ICD Disease Classification 2C82.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Androgen receptor (AR) DTT AR 2.13E-01 -0.07 -0.11
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Nat Rev Drug Discov. 2013 Feb;12(2):87-90.
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015